With obesity on the rise, a variety of oral treatments are now obtainable in the market. But ‘how to opt for an effective obesity management?’ is the question that prevails in our mind.
Mr. Robert Parker, a senior marketing executive at Online Adipex comments, “in the midst of the a range of medications presented in the market, Adipex diet drug has emerged as one of the preferred diet supplement to an entire weight loss schedule facilitate weight loss. It is a short-term treatment which is employed by many obese to fetch effective weight loss”.
Adipex: HOW SUPPLIED
Available in tablets and capsules containing 37.5 mg phentermine
hydrochloride (equivalent to 30 mg phentermine base). Each blue and
white, oblong, scored tablet is debossed with “ADIPEX-P” and “9”-“9”.
The #3 capsule has an opaque white body and an opaque bright blue cap.
Each capsule is imprinted with “ADIPEX-P” - “37.5” on the cap and two
stripes on the body using dark blue ink.
Tablets are packaged in bottles of 30 (NDC 57844-009-56); 100 (NDC 57844-009-01); and 1000 (NDC 57844-009-10).
Adipex: DOSAGE AND ADMINISTRATION
Exogenous Obesity: Dosage should be individualized to obtain an
adequate response with the lowest effective dose. The usual adult dose
is one capsule or tablet (37.5 mg) daily, administered before breakfast
or 1-2 hours after breakfast. For tablets, the dosage may be adjusted
to the patient’s need. For some patients 1/2 tablet (18.75 mg) daily
may be adequate, while in some cases it may be desirable to give 1/2
tablet (18.75 mg) two times a day.
Late evening medication should be avoided because of the possibility of resulting insomnia.
Phentermine is not recommended for use in patients sixteen (16) years of age and under.
ADVERSE REACTIONS
Cardiovascular: Primary pulmonary hypertension and/or regurgitant
cardiac valvular disease, palpitation, tachycardia, elevation of blood
pressure.
Central Nervous System: Overstimulation, restlessness, dizziness,
insomnia, euphoria, dysphoria, tremor, headache; rarely psychotic
episodes at recommended doses.
ADIPEX: DRUG ABUSE AND DEPENDENCE
ADIPEX-P® is related chemically and pharmacologically to the
amphetamines. Amphetamines and related stimulant drugs have been
extensively abused, and the possibility of abuse of ADIPEX-P® should be
kept in mind when evaluating the desirability of including a drug as
part of a weight reduction program. Abuse of amphetamines and related
drugs may be associated with intense psychological dependence and
severe social dysfunction. There are reports of patients who have
increased the dosage to many times that recommended. Abrupt cessation
following prolonged high dosage administration results in extreme
fatigue and mental depression; changes are also noted on the sleep EEG.
Manifestations of chronic intoxication with anorectic drugs include
severe dermatoses, marked insomnia, irritability, hyperactivity and
personality changes. The most severe manifestation of chronic
intoxications is psychosis, often clinically indistinguishable from
schizophrenia.
ADIPEX: INDICATIONS AND USAGE
ADIPEX-P®
(phentermine
hydrochloride) is indicated as a short-term (a few weeks) adjunct in a
regimen of weight reduction based on exercise, behavioral modification
and caloric restriction in the management of exogenous obesity for
patients with an initial body mass index ≥30 kg/m2, or ≥27 kg/m2 in the
presence of other risk factors (e.g., hypertension, diabetes,
hyperlipidemia).
ADIPEX-P® (Phentermine Hydrochloride USP, 37.5 mg)
DESCRIPTION
Phentermine hydrochloride USP has the chemical name of _,_-Dimethylphenethylamine hydrochloride. The structural formula is as follows:
C10H15N • HCl M.W. 185.7
Phentermine hydrochloride is a white, odorless, hygroscopic, crystalline powder which is soluble in water and lower alcohols, slightly soluble in chloroform and insoluble in ether.
ADIPEX-P®, an anorectic agent for oral administration, is available as a capsule or tablet containing 37.5 mg of phentermine hydrochloride (equivalent to 30 mg of phentermine base).
ADIPEX-P® Capsules contain the inactive ingredients Corn Starch, Gelatin, Lactose Monohydrate, Magnesium Stearate, Titanium Dioxide, Black Iron Oxide, FD&C Blue #1, FD&C Red #40 and D&C Red #33.
ADIPEX-P® Tablets contain the inactive ingredients Corn Starch, Lactose (Anhydrous), Magnesium Stearate, Microcrystalline Cellulose, Pregelatinized Starch, Sucrose, and FD&C Blue #1.
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