Phentermine: Mecanism of action ↓

• Adipex P (Immediate release)
• Anoxine-AM®                       
  

• Fastin® (discontinued)

• Ionamin® (Slow Release Resin, Australia, discontinued in the US)
• Duromine® (Slow Release Resin, New Zealand)
• Obephen®   
  
• Obermine®  
  
• Obestin-30®
• Phentrol®    
  

• Phenterex®
• Phentromin®
• Pro-Fast SA
• Redusa       
  
• Panbesy     
  
• Phentermine Trenker
• Obenix      
  
• Oby-Trim  
  

Mechanism of action

Phentermine, like many other prescription drugs, works with neurotransmitters in the brain. It is a centrally-acting stimulant and is a constitutional isomer (not to be confused with stereoisomer) of methamphetamine. It stimulates neuron bundles to release a particular group of neurotransmitters known as catecholamines; these include dopamine, epinephrine (also known as adrenalin), and norepinephrine (noradrenaline). The anorectic activity seen with these compounds is thus likely due to their effect on the central nervous system, which is consistent with current knowledge about the central nervous system and feeding behavior. This is the same mechanism of action as other stimulant appetite suppressants such as diethylpropion and phendimetrazine. The neurotransmitters signal a fight-or-flight response in the body which, in turn, puts a halt to the hunger signal. As a result, it causes a loss in appetite because the brain does not receive the hunger message.